J Korean Diabetes.  2018 Jun;19(2):76-81. 10.4093/jkd.2018.19.2.76.

Environmental Pollution and Diabetes

• Kim JH

• KMID: 2415850
• DOI: http://doi.org/10.4093/jkd.2018.19.2.76

Abstract

Endocrine disrupting chemicals (EDCs) are exogenous chemicals contained in industrial substances and plasticizers commonly utilized worldwide. Human exposure to such chemicals, particularly at low-doses, is omnipresent, persistent, and occurs in complex mixtures. EDCs include bisphenol A, phthalates, pesticides, and persistent organic pollutants such as polychlorinated biphenyls. Burgeoning epidemiological, animal, and cellular data link environmental EDCs to metabolic dysfunction. In the last three decades, the number of diabetic patients has drastically increased worldwide, with current statistics suggesting that the number will double in the next two decades. There is epidemiological and experimental evidence linking background exposure to a selection of environmental EDCs with diabetes and impaired glucose metabolism. EDC may be related to increased risk of diabetes.

Keyword

Diabetes; Endocrine disruptors; Environmental pollution

MeSH Terms

Animals
Complex Mixtures
Endocrine Disruptors
Environmental Pollution*
Glucose
Humans
Metabolism
Pesticides
Plasticizers
Plastics
Polychlorinated Biphenyls
Complex Mixtures
Endocrine Disruptors
Glucose
Pesticides
Plasticizers
Plastics
Polychlorinated Biphenyls

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