Korean J Vet Res.  2018 Jun;58(2):87-94. 10.14405/kjvr.2018.58.2.87.

Oral malodor-reducing effects by oral feeding of Weissella cibaria CMU in Beagle dogs

• Do KH
• Park HE
• Kang MS
• Kim JT
• Yeu JE
• Lee WK

• KMID: 2414717
• DOI: http://doi.org/10.14405/kjvr.2018.58.2.87

Abstract

This study assessed the effects of Weissella cibaria (W. cibaria) CMU on oral health in male and female beagles (n = 18) by measuring oral malodor and periodontal disease-related parameters (calculus, plaque, and gingivitis indices). Oral malodor and indicators of periodontal disease were assessed in five treatment groups: negative control (scaling and 0.24 mg of maltodextrin, n = 3), positive control (0.24 mg of maltodextrin, n = 3), and W. cibaria CMU groups (each n = 4) at low (CMU-L, 2 × 10⁷ colony forming unit [CFU]), medium (CMU-M, 2 × 10⁸ CFU), and high (CMU-H, 2 × 10⁹ CFU) concentrations. After feeding with W. cibaria CMU for 6 weeks, total volatile sulfur compound concentrations in the CMU-L (2.0 ± 1.04 ng/10 mL), CMU-M (2.4 ± 1.05 ng/10 mL), and CMU-H (2.6 ± 1.33 ng/10 mL)groups were significantly lower than in the positive control group (3.2 ± 1.65 ng/10 mL). Also, CMU-L (1.4 ± 0.83 ng/10 mL) and CMU-H (1.9 ± 1.14 ng/10 mL) groups had methyl mercaptan levels lower than that in the positive control group (2.4 ± 1.21 ng/10 mL) at week 2. The plaque index was significantly lower in the CMU-H group (4.5 ± 0.28) than in the positive control group (5.9 ± 1.08) at week 6. W. cibaria CMU could be useful as a novel oral hygiene probiotics for reducing volatile sulfur compounds production and inhibiting plaque growth in companion animals.

Keyword

Beagle; Weissella cibaria CMU; methyl mercaptan; oral malodor; plaque index

MeSH Terms

Animals
Dogs*
Female
Gingivitis
Humans
Male
Oral Health
Oral Hygiene
Periodontal Diseases
Pets
Probiotics
Stem Cells
Sulfur
Sulfur Compounds
Weissella*
Sulfur
Sulfur Compounds