J Korean Assoc Oral Maxillofac Surg.  2018 Jun;44(3):107-111. 10.5125/jkaoms.2018.44.3.107.

Retrospective clinical study of multiple keratocystic odontogenic tumors in non-syndromic patients

• Hwang DS
• Kim YH
• Kim UK
• Ryu MH
• Kim GC

• KMID: 2414429
• DOI: http://doi.org/10.5125/jkaoms.2018.44.3.107

Abstract

OBJECTIVES
A keratocystic odontogenic tumor (KOT) is a type of odontogenic tumor that mainly occurs in the posterior mandible. Most KOTs appear as solitary lesions; however, they sometimes occur as multiple cysts. This study analyzed the clinical features of multiple KOTs.
MATERIALS AND METHODS
The participants were diagnosed with KOT by biopsy with multiple surgical sites, and were patients at the Pusan National University Hospital and the Pusan National University Dental Hospital from January 1, 2005 to March 31, 2016. Charts, records, images and other findings were reviewed.
RESULTS
A total of 31 operations were conducted in 17 patients. The mean patient age was 28.4±20.1 years. Multiple KOTs were found to occur at a young age (P<0.01). The predominant sites were in the posterior mandible (28.6%). Most cases of multiple lesions appeared in both the upper and lower jaw, and 40.3% of lesions were associated with unerupted and impacted teeth. The overall recurrence rate measured by operation site was 10.4% (8/77 sites). No patients were associated with nevoid basal cell carcinoma syndrome.
CONCLUSION
The pure recurrence rate was lower than estimated, but there was a higher possibility of secondary lesions regardless of the previous operation site; therefore, long-term follow-up is necessary.

Keyword

Keratocystic odontogenic tumor; Odontogenic keratocyst; Odontogenic cyst; Keratocyst

MeSH Terms

Basal Cell Nevus Syndrome
Biopsy
Busan
Clinical Study*
Follow-Up Studies
Humans
Jaw
Mandible
Odontogenic Cysts*
Odontogenic Tumors*
Recurrence
Retrospective Studies*
Tooth, Impacted

Figure

• 

  Fig. 1 Frequency of operations for each patient. Patients had an average of 1.82 operations, including surgeries due to recurrence. One patient had four operations, which was the maximum number of operations per person.

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