J Korean Soc Matern Child Health.  2018 May;22(2):106-111. 10.21896/jksmch.2018.22.2.106.

Risk Factors for Preterm Birth in Advanced Maternal Age

• Kwon EJ
• Lee KJ
• Cho A
• Park S
• Park MH
• Kim YJ
• The Korean Preterm Collaborate Network Group

• KMID: 2412465
• DOI: http://doi.org/10.21896/jksmch.2018.22.2.106

Abstract

PURPOSE
To identify the potential risk factors for preterm birth (PTB) in women with advanced maternal age in the Korean population.
METHODS
We selected the data of 531 pregnant women and singletons in the Korean Preterm Collaborate Network Study. Among the data, we analyzed variables related to demographic characteristics, lifestyle factors, and delivery information. Maternal age was divided into two groups: younger ( < 35 years) and advanced (≥35 years). Multiple logistic regression analysis was performed to identify the potential risk factors for PTB in advanced maternal age.
RESULTS
In advanced maternal age, education level, occupation, passive smoking, iron intake, and parity showed significant differences between term birth and PTB. In particular, women who were exposed to passive smoking (odds ratio [OR]=2.83, confidence interval [CI]=1.14~7.04) and had folic acid intake during pregnancy (OR=2.67, CI=1.11~6.43) were at a significantly increased risk of PTB, after adjusting for all variables.
CONCLUSION
This study indicates that smoking and lifestyle factors are the potential risk factors for PTB in advanced maternal age.

Keyword

Advanced maternal age; premature birth; pregnancy; smoking; lifestyle

MeSH Terms

Education
Female
Folic Acid
Humans
Iron
Life Style
Logistic Models
Maternal Age*
Occupations
Parity
Pregnancy
Pregnant Women
Premature Birth*
Risk Factors*
Smoke
Smoking
Term Birth
Tobacco Smoke Pollution
Folic Acid
Iron
Smoke
Tobacco Smoke Pollution