Gut Liver.  2016 May;10(3):375-381. 10.5009/gnl15254.

The Performance of a Modified Glasgow Blatchford Score in Predicting Clinical Interventions in Patients with Acute Nonvariceal Upper Gastrointestinal Bleeding: A Vietnamese Prospective Multicenter Cohort Study

Affiliations
  • 1Department of Internal Medicine, University of Medicine and Pharmacy, Hochiminh City Vietnam. drquachtd@ump.edu.vn
  • 2Department of Gastroenterology, Gia-Dinh People's Hospital, Ho Chi Minh, Vietnam.
  • 3Department of Gastroenterology, An-Binh Hospital, Ho Chi Minh, Vietnam.
  • 4Department of Gastroenterology, Dong-Nai General Hospital, Ho Chi Minh, Vietnam.
  • 5Department of Gastroenterology, Trung-Vuong Emergency Center, Ho Chi Minh, Vietnam.
  • 6Department of Gastroenterology, Nguyen-Tri-Phuong Hospital, Ho Chi Minh, Vietnam.
  • 7Health Service Center, Hiroshima University, Higashihiroshima, Japan.

Abstract

BACKGROUND/AIMS
To compare the performance of a modified Glasgow Blatchford score (mGBS) to the Glasgow Blatchford score (GBS) and the pre-endoscopic Rockall score (RS) in predicting clinical interventions in Vietnamese patients with acute nonvariceal upper gastrointestinal bleeding (AN-VUGIB).
METHODS
A prospective multicenter cohort study was conducted in five tertiary hospitals from May 2013 to February 2014. The mGBS, GBS, and pre-endoscopic RS scores were prospectively calculated for all patients. The accuracy of mGBS was compared with that of GBS and pre-endoscopic RS using area under the receiver operating characteristic curve (AUC). Clinical interventions were defined as blood transfusions, endoscopic or radiological intervention, or surgery.
RESULTS
There were 395 patients including 128 (32.4%) needing endoscopic treatment, 117 (29.6%) requiring blood transfusion and two (0.5%) needing surgery. In predicting the need for clinical intervention, the mGBS (AUC, 0.707) performed as well as the GBS (AUC, 0.708; p=0.87) and outperformed the pre-endoscopic RS (AUC, 0.594; p<0.001). However, none of these scores effectively excluded the need for endoscopic intervention at a threshold of 0.
CONCLUSIONS
mGBS performed as well as GBS and better than pre-endoscopic RS for predicting clinical interventions in Vietnamese patients with ANVUGIB.

Keyword

Gastrointestinal hemorrhage; Prediction score; Prognosis; Vietnamese

MeSH Terms

Acute Disease
Area Under Curve
Endoscopy, Gastrointestinal/methods
Gastrointestinal Hemorrhage/*diagnosis
Humans
Male
Middle Aged
Prospective Studies
*Severity of Illness Index
Vietnam
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