Psychiatry Investig.  2018 Feb;15(2):141-146. 10.30773/pi.2017.10.11.

Longitudinal Impact of Depression on Quality of Life in Stroke Patients

• Kim ES
• Kim JW
• Kang HJ
• Bae KY
• Kim SW
• Kim JT
• Park MS
• Cho KH
• Kim JM

• KMID: 2409422
• DOI: http://doi.org/10.30773/pi.2017.10.11

Abstract

OBJECTIVE
Stroke is associated with significant long-term morbidity and poor quality of life (QOL). Depression is one of the most common complications after stroke and has been associated with QOL cross-sectionally. We investigated the longitudinal impact of depression in the acute phase of stroke on QOL 1 year after stroke.
METHODS
In total, 423 patients were evaluated 2 weeks after stroke, and 288 (68%) were followed 1 year later. QOL was assessed using the World Health Organization Quality of Life-Abbreviated form (WHOQOL-BREF) at baseline and follow-up. Depression was diagnosed according to Diagnostic and Statistical Manual of Mental Disorders-IV criteria; demographic and clinical characteristics data, including stroke severity, were obtained at baseline. The longitudinal associations of post-stroke depression (PSD) at baseline with QOL across two evaluation points were assessed using a repeated-measures analysis of variance.
RESULTS
The WHOQOL-BREF scores were significantly and persistently lower 1 year after stroke in patients with PSD at baseline compared with those without PSD at baseline independent of demographic and clinical characteristics, including stroke severity.
CONCLUSION
PSD in the acute phase of stroke is an independent predictor of QOL in both the acute and chronic phases of stroke. Our findings underscore the importance of evaluating depression in the acute phase of stroke.

Keyword

Stroke; Depression; Longitudinal study; Quality of life; Outcome assessment

MeSH Terms

Depression*
Follow-Up Studies
Humans
Longitudinal Studies
Quality of Life*
Stroke*
World Health Organization