J Clin Neurol.  2018 Apr;14(2):251-253. 10.3988/jcn.2018.14.2.251.

Self-Injurious Behavior Revealing Advanced Primary Progressive Multiple Sclerosis with a Massive Right Temporal Lesion

• Gschwind M
• Lascano AM
• Kaya G
• Assal F

• KMID: 2407957
• DOI: http://doi.org/10.3988/jcn.2018.14.2.251

Abstract

No abstract available.

MeSH Terms

Multiple Sclerosis, Chronic Progressive*
Self-Injurious Behavior*

Figure

• 

  Fig. 1 The patient's arms, hands, and fingers were covered with hyperkeratotic skin lesions consistent with lichen simplex chronicus.

• 

  Fig. 2 Magnetic resonance imaging of the patient's brain. A: Transverse T2-weighted images show an extensive periventricular white-matter damage in the right temporal lobe (arrows). B: Sagittal FLAIR images show multiple demyelinating lesions juxtacortical in the corpus callosum, pons, midbrain, and cerebellum (arrows). C: T1-weighted images with Gd+ show lesions with contrast enhancement (arrows). Images displayed in accordance with the usual radiological convention. FLAIR: fluid attenuated inversion recovery.

Reference

1. Stein DJ, Zohar J, Simeon D. Compulsive and impulsive aspects of self-injourious behavior. In : Davis KL, Charney D, Coyle JT, Nemeroff C, editors. Neuropsychopharmacology: The Fifth Generation of Progress-An Official Publication of the American College of Neuropsychopharmacolog. Philadelphia, PA: Lippincott Williams & Wilkins;2002. p. 1743–1758.

2. Mendez MF, Bagert BA, Edwards-Lee T. Self-injurious behavior in frontotemporal dementia. Neurocase. 1997; 3:231–236.

3. Critchley HD, Simmons A, Daly EM, Russell A, van Amelsvoort T, Robertson DM, et al. Prefrontal and medial temporal correlates of repetitive violence to self and others. Biol Psychiatry. 2000; 47:928–934.

4. Tinelli E, Francia A, Quartuccio EM, Morreale M, Contessa GM, Pascucci S, et al. Structural brain MR imaging changes associated with obsessive-compulsive disorder in patients with multiple sclerosis. AJNR Am J Neuroradiol. 2013; 34:305–309.

5. Borah S, McConnell B, Hughes R, Kluger B. Potential relationship of self-injurious behavior to right temporo-parietal lesions. Neurocase. 2016; 22:269–272.