Blood Res.  2017 Dec;52(4):326-329. 10.5045/br.2017.52.4.326.

Differential diagnosis of primary cutaneous CD4+ small/medium T-cell lymphoproliferative lesions: A report of three cases

• Kim HJ
• Han JH
• Min SK

• KMID: 2405074
• DOI: http://doi.org/10.5045/br.2017.52.4.326

Abstract

No abstract available.

MeSH Terms

Diagnosis, Differential*
T-Lymphocytes*

Figure

• 

  Fig. 1 Patient (No. 1) presented a reddish nodule on the scalp, measuring 2.7 cm in the greatest dimension. The outer surface showed no ulceration.

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  Fig. 2 (A) Scanning microscopy showed a nodular mass, occupying the entire dermis and subcutis along the fascia (Hematoxylin-Eosin stain, ×10). (B) The epidermis showed no definite epidermotropism with a subepidermal grenz zone (Hematoxylin-Eosin stain, ×40). (C) The cells are bland-looking, small-to-medium-sized lymphocytes (Hematoxylin-Eosin stain, ×400). The tumor cells are positive for CD3 (D) and CD4 (E) and negative for CD20 (F) and CD8 (G), indicating a helper T-cell phenotype. Tumor cells are also positive for PD1 (H) and CXCL13 (I), suggestive of a follicular helper T-cell phenotype. The Ki-67 proliferative index was low at 10% (J).

Reference

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