J Prev Med Public Health.  2018 Jan;51(1):15-22. 10.3961/jpmph.17.118.

Identifying Adverse Events Using International Classification of Diseases, Tenth Revision Y Codes in Korea: A Cross-sectional Study

Affiliations
  • 1Department of Preventive Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.
  • 2Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, Korea. leems@amc.seoul.kr
  • 3Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul, Korea.

Abstract


OBJECTIVES
The use of administrative data is an affordable alternative to conducting a difficult large-scale medical-record review to estimate the scale of adverse events. We identified adverse events from 2002 to 2013 on the national level in Korea, using International Classification of Diseases, tenth revision (ICD-10) Y codes.
METHODS
We used data from the National Health Insurance Service-National Sample Cohort (NHIS-NSC). We relied on medical treatment databases to extract information on ICD-10 Y codes from each participant in the NHIS-NSC. We classified adverse events in the ICD-10 Y codes into 6 types: those related to drugs, transfusions, and fluids; those related to vaccines and immunoglobulin; those related to surgery and procedures; those related to infections; those related to devices; and others.
RESULTS
Over 12 years, a total of 20 817 adverse events were identified using ICD-10 Y codes, and the estimated total adverse event rate was 0.20%. Between 2002 and 2013, the total number of such events increased by 131.3%, from 1366 in 2002 to 3159 in 2013. The total rate increased by 103.9%, from 0.17% in 2002 to 0.35% in 2013. Events related to drugs, transfusions, and fluids were the most common (19 446, 93.4%), followed by those related to surgery and procedures (1209, 5.8%) and those related to vaccines and immunoglobulin (72, 0.3%).
CONCLUSIONS
Based on a comparison with the results of other studies, the total adverse event rate in this study was significantly underestimated. Improving coding practices for ICD-10 Y codes is necessary to precisely monitor the scale of adverse events in Korea.

Keyword

Adverse event; International Classification of Diseases; Administrative claims; Healthcare; Republic of Korea

MeSH Terms

Clinical Coding
Cohort Studies
Cross-Sectional Studies*
Delivery of Health Care
Immunoglobulins
International Classification of Diseases*
Korea*
National Health Programs
Republic of Korea
Vaccines
Immunoglobulins
Vaccines
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