Korean J Fam Med.  2018 Jan;39(1):51-53. 10.4082/kjfm.2018.39.1.51.

A Possible Case of Statin-Induced Ichthyosis in an Elderly Woman

Affiliations
  • 1Department of Family Medicine, Gachon University Gil Medical Center, Incheon, Korea. zaduplum@gilhospital.com
  • 2Department of Dermatology, Gachon University Gil Medical Center, Incheon, Korea.

Abstract

Ichthyosis is a heterogeneous group of hereditary or acquired skin disorders, characterized by increased stratum corneum production. Several systemic diseases and many drugs can occasionally cause acquired ichthyosis. We report a case of statin-induced ichthyosis in which the causality between statin and ichthyosis was found possible by using the Naranjo scale. A 79-year-old woman presented with pruritic skin lesions on both legs that appeared erythematous, scaly, and cracked. A clinical diagnosis of acquired ichthyosis was made and the statin was suspected as the cause. The skin lesions improved after 6 weeks of dose reduction of the statin.

Keyword

Hydroxymethylglutaryl-CoA Reductase Inhibitors; Statin; Ichthyosis; Skin

MeSH Terms

Aged*
Diagnosis
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Ichthyosis*
Leg
Skin
Hydroxymethylglutaryl-CoA Reductase Inhibitors
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