Korean J Fam Med.  2018 Jan;39(1):51-53. 10.4082/kjfm.2018.39.1.51.

A Possible Case of Statin-Induced Ichthyosis in an Elderly Woman

• Ko KD
• Kim KK
• Baek JO
• Suh HS
• Hwang IC

• KMID: 2401724
• DOI: http://doi.org/10.4082/kjfm.2018.39.1.51

Abstract

Ichthyosis is a heterogeneous group of hereditary or acquired skin disorders, characterized by increased stratum corneum production. Several systemic diseases and many drugs can occasionally cause acquired ichthyosis. We report a case of statin-induced ichthyosis in which the causality between statin and ichthyosis was found possible by using the Naranjo scale. A 79-year-old woman presented with pruritic skin lesions on both legs that appeared erythematous, scaly, and cracked. A clinical diagnosis of acquired ichthyosis was made and the statin was suspected as the cause. The skin lesions improved after 6 weeks of dose reduction of the statin.

Keyword

Hydroxymethylglutaryl-CoA Reductase Inhibitors; Statin; Ichthyosis; Skin

MeSH Terms

Aged*
Diagnosis
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Ichthyosis*
Leg
Skin
Hydroxymethylglutaryl-CoA Reductase Inhibitors