Investig Magn Reson Imaging.  2017 Dec;21(4):269-272. 10.13104/imri.2017.21.4.269.

Periductal Stromal Sarcoma of the Breast: a Case Report

• Kim YH
• Lee JY
• Kim YM

• KMID: 2400382
• DOI: http://doi.org/10.13104/imri.2017.21.4.269

Abstract

Periductal stromal sarcoma (PSS) is a type of rare malignant fibroepithelial tumor. PSS is a recently introduced diagnostic entity and there are few reports about radiological features of this tumor. Pre-operative diagnosis is difficult because it reveals similar symptoms with other benign and malignant tumors with absence of specific radiologic findings. We present a woman age 30 that underwent mammotome biopsy for a BI-RADS 4 lesion on her left breast and received histopathology diagnosis of a phyllodes tumor. Additionally, she underwent a wide excision depending on her histopathology diagnosis. Her final diagnosis was PSS. Six months later, no recurrence was detected. However, frequent follow-up is needed because PSS can develop into phyllodes tumor or entity of breast cancer.

Keyword

Periductal stromal sarcoma; Breast; Magnetic resonance imaging

MeSH Terms

Biopsy
Breast Neoplasms
Breast*
Diagnosis
Female
Follow-Up Studies
Humans
Magnetic Resonance Imaging
Phyllodes Tumor
Recurrence
Sarcoma*

Figure

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  Fig. 1 (a) Mammogram mediolateral oblique (MLO) view reveals extremely dense breasts that make it difficult to evaluate the mass lesion. (b) Ultrasonographic image reveals oval mass in parallel orientation with angular margins in upper outer quadrant of the left breast.

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  Fig. 2 On MRI of breasts after mammotome excision, a 6 mm-sized irrgular shaped mass (arrow), revealing high signal intensity on fat-saturated T2-weighted image (a) with homogeneous enhancement (arrow) on first dynamic enhancement study (90 seconds) (b) was found in upper outer quadrant of the left breast.

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  Fig. 3 On pathology examination, (a) low-power field (× 40) and (b) high-power field (× 200) images of the tumor reveal biphasic proliferation and a multinodular growth pattern and was composed of spindle cells without significant atypia, cuff formations around open tubules without leaf-like pattern. (c) On immunohistochemistry staining, stromal cells were positive with CD34 and (d) negative with S100.

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