World J Mens Health.
2017 Dec;35(3):205-208. 10.5534/wjmh.17015.
Male Infertility Associated with a Supernumerary Marker Chromosome
- Affiliations
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- 1Department of Urology, CHA Gangnam Medical Center, CHA University, Seoul, Korea. dskim100@chamc.co.kr
- 2Department of Genetics, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
- 3Department of Pathology, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
- 4Fertility Center, CHA Gangnam Medical Center, CHA University, Seoul, Korea.
- 5Department of Urology, Yonsei University, Wonju College of Medicine, Wonju, Korea.
- KMID: 2398570
- DOI: http://doi.org/10.5534/wjmh.17015
Abstract
- A marker chromosome (mar) is a structurally abnormal chromosome in which no part can be identified. The significance of a marker varies, depending on the material contained within the marker. Very few reports have been published of marker chromosomes associated with male infertility. Here, we report the case of an infertile man with a rare variant of a marker chromosome of a mos 47,XY,+mar[25]/46,XY[25] karyotype.
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