Korean J Ophthalmol.  2017 Dec;31(6):514-523. 10.3341/kjo.2016.0098.

Epiretinal Membrane: Prevalence and Risk Factors from the Korea National Health and Nutrition Examination Survey, 2008 through 2012

Affiliations
  • 1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. swkang@skku.edu
  • 2Department of Ophthalmology, Kyungpook National University Hospital, Daegu, Korea.
  • 3Department of Ophthalmology, SMG-SNU Boramae Medical Center, Seoul, Korea.
  • 4Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Abstract

PURPOSE
To investigate the prevalence and risk factors for an epiretinal membrane (ERM) in Korean population.
METHODS
Using the database of the Korea National Health and Nutrition Examination Survey from 2008 through 2012, 14,772 participants 40 years of age or older with gradable fundus photographs were included. The presence of ERM was determined by using fundus photographs. The prevalence of ERM was estimated and possible risk factors including systemic factors, nutritional status, and blood tests were analyzed via multiple logistic regression analyses.
RESULTS
The prevalence of ERM was 2.9% (95% confidence interval [CI], 2.6% to 3.3%). On multiple logistic regression analysis, the prevalence of ERM was affected by age. The odds ratios (ORs) against the forties were 2.70, 5.48, and 5.69 in the fifties, sixties, and seventies, respectively. ERM was also significantly affected by cataract surgery (OR, 2.82; 95% CI, 2.08 to 3.81) and by the increase in intake of 100-mg calcium (OR, 1.05; 95% CI, 1.00 to 1.11). ERM had negative associations with red blood cell count (OR, 0.66; 95% CI, 0.45 to 0.95).
CONCLUSIONS
The estimated nation-wide prevalence of ERM in Korea is 2.9%. The presence of ERM in the general population is associated with age, cataract surgery, increased dietary calcium, and a low red blood cell count.

Keyword

Epiretinal membrane; Korea National Health and Nutrition Examination Survey; Prevalence; Risk factors

MeSH Terms

Calcium
Calcium, Dietary
Cataract
Epiretinal Membrane*
Erythrocyte Count
Hematologic Tests
Korea*
Logistic Models
Nutrition Surveys*
Nutritional Status
Odds Ratio
Prevalence*
Risk Factors*
Calcium
Calcium, Dietary

Figure

  • Fig. 1 Flow chart of subjects excluded and included for analysis in the current study. KHNANES = Korea National Health and Nutrition Examination Survey; ERM = epiretinal membrane.

  • Fig. 2 Cumulative frequency of visual acuity in the eyes with an epiretinal membrane.

  • Fig. 3 Forest plot in the multiple logistic regression model for risk factors of epiretinal membrane.


Cited by  1 articles

Clinical Outcomes of Idiopathic Epiretinal Membrane Removal in Patients 80 Years or Older
Jae Wook Han, Jong Woo Kim, Chul Gu Kim, Dong Won Lee, Su Jin Yoo, Moon Jung Choi, Young Ju Lew, Hyung Seok Kim, Han Joo Cho, Ju Yeon Kim, Jae Hui Kim
J Korean Ophthalmol Soc. 2020;61(2):159-166.    doi: 10.3341/jkos.2020.61.2.159.


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