Nucl Med Mol Imaging.  2017 Sep;51(3):274-276. 10.1007/s13139-016-0420-2.

Unusual Soft Tissue Uptake of F-18 Sodium Fluoride in Three Patients Undergoing F-18 NaF PET/CT Bone Scans for Prostate Cancer

• Hawkins AS
• Howard BA

• KMID: 2396589
• DOI: http://doi.org/10.1007/s13139-016-0420-2

Abstract

Three males aged 71 to 80 years with known stage IV metastatic prostate cancer underwent F-18 sodium fluoride (NaF) PET/CT to assess osseous metastatic disease burden and stability. In addition to F-18 NaF avid known osseous metastases, each patient also exhibited increased F-18 NaF activity in soft tissues. The first patient exhibited multiple F-18 NaF avid enlarged retroperitoneal and pelvic lymph nodes on consecutive PET/CT scans. The second patient demonstrated an F-18 NaF avid thyroid nodule on consecutive PET/CT scans. The third patient exhibited increased F-18 NaF activity in a hepatic metastasis.

Keyword

F-18NaF; Sodiumfluoride; PET/CT; Soft tissue; Prostate cancer

MeSH Terms

Humans
Lymph Nodes
Male
Neoplasm Metastasis
Positron-Emission Tomography and Computed Tomography*
Prostate*
Prostatic Neoplasms*
Sodium Fluoride*
Sodium*
Thyroid Nodule
Sodium
Sodium Fluoride