Child Kidney Dis.  2017 Oct;21(2):156-159. 10.3339/jkspn.2017.21.2.156.

Severe Hypophosphatemia in a Girl with Systemic Lupus Erythematosus

Affiliations
  • 1Department of Pediatrics, Pusan National University Children's Hospital, Yangsan, Gyeongnam, Republic of Korea. pedksh@gmail.com

Abstract

Systemic lupus erythematosus (SLE) is characterized by various symptoms and multi-organ involvement. Hypophosphatemia has been described in several diseases accompanied with systemic inflammation. However, hypophosphatemia has rarely been described in SLE patients, especially in those without nephritis. We report the case of a 13-year-old girl with SLE who developed hypophosphatemia without renal involvement. Her hypophosphatemia was caused by renal loss of phosphorus and persisted for 7 months. It improved as her complement levels increased. Therefore, hypophosphatemia may be related to disease activity in SLE patients.

Keyword

Systemic lupus erythematosus; Hypophosphatemia; Renal loss

MeSH Terms

Adolescent
Complement System Proteins
Female*
Humans
Hypophosphatemia*
Inflammation
Lupus Erythematosus, Systemic*
Nephritis
Phosphorus
Complement System Proteins
Phosphorus
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