Obstet Gynecol Sci.  2017 Sep;60(5):494-497. 10.5468/ogs.2017.60.5.494.

A case report of angioleiomyoma of uterus

Affiliations
  • 1Department of Obstetrics and Gynecology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. guardc@schmc.ac.kr
  • 2Department of Pathology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.

Abstract

Angioleiomyoma (AL) is a very rare benign tumor that originates from smooth muscle cells and has thick walled vessels. It may be found throughout the body but more frequently occurs in the lower extremities and rarely develops in the head and other parts of the body. This paper presents a case report of giant AL detected in a 33-year-old woman who complained of severe anemia, menorrhagia, and palpable lower abdominal mass. The patient underwent myomectomy and was diagnosed with AL based on the pathological report of mass. The effective treatment for AL is either simple hysterectomy or angiomyomectomy depending on the patient's desire to preserve fertility and symptom.

Keyword

Angioleiomyoma; Leiomyoma; Immunohistochemistry; Uterus

MeSH Terms

Adult
Anemia
Angiomyoma*
Female
Fertility
Head
Humans
Hysterectomy
Immunohistochemistry
Leiomyoma
Lower Extremity
Menorrhagia
Myocytes, Smooth Muscle
Uterus*

Figure

  • Fig. 1 (A) Computed tomography shows 14.2 cm huge uterine myoma with endometrial compression, (B) transabdominal ultrasound sonography shows huge myoma found anterior to the uterus, and (C) gross findings show a 12.5×9.0 cm2 sized gray firm mass after the operation. UT, uterus.

  • Fig. 2 (A) Microscopic findings indicate the tumor with interlacing short spindle cells and numerous thick walled vessels (hematoxylin and eosin stain, ×40), (B) immunohistochemical stain of smooth muscle actin (SMA) reveals diffuse positivity in the spindle tumor cells and swirling cells around the thick-walled blood vessels (immunohistochemistry of SMA, ×100).


Reference

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