Korean J Obstet Gynecol.  2012 Oct;55(10):782-786.

Primary squamous cell carcinoma arising from the pelvic retroperitoneum

Affiliations
  • 1Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea. yuni105@korea.ac.kr

Abstract

Primary retroperitoneal squamous cell carcinoma is very rare. A 66-year-old woman presented with right leg edema and pain that had developed one month prior. Pelvis magnetic resonance imaging showed the presence of a mass around the iliac vessels invading the iliacus muscle, right femoral head and obturator muscle. The patient underwent an exploratory laparotomy but the mass was not completely removed. The patient was treated with concurrent chemoradiation therapy with paclitaxel-carboplatin and Tomotherapy three weeks after surgery. After that, she conducted a further seven cycles of different chemotherapy. A abdomen CT scan after the last seven cycles showed a reduction in the size of the primary mass from 7.2 to 6.6 cm, consistent with a partial response to treatment. As a result, the role of adjuvant chemotherapy in these tumors is controversial. And it is considered that complete resection is more important.

Keyword

Primary retroperitoneal neoplasms; Squamous cell carcinoma; Concurrent chemoradiation therapy

MeSH Terms

Abdomen
Aged
Carcinoma, Squamous Cell
Chemotherapy, Adjuvant
Edema
Female
Head
Humans
Laparotomy
Leg
Magnetic Resonance Imaging
Muscles
Pelvis

Figure

  • Fig. 1 Magnetic resonance imaging showed the presence of a heterogeneous mass with an ill-defined margin that measured 7.2 cm. Focal calcification that infiltrated the iliacus muscle, femoral head and obturator muscle was observed.

  • Fig. 2 Microscopic findings of the tumor are shown. A squamous cell carcinoma with intercellular bridges and island infiltrating fibrous tissue is seen (H&E, ×200).

  • Fig. 3 18F-fluorodeoxyglucose positron emission tomography showed the presence of a hypermetabolic residual tumor at the right common iliac and pelvic region with invasion to the right acetabulum.


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