J Korean Soc Radiol.  2017 Oct;77(4):237-240. 10.3348/jksr.2017.77.4.237.

An Unusual Imaging Finding of Breast Metastasis from Rhabdomyosarcoma

• Ko Y
• Lee JE
• Chung J
• Kim JH
• Chae IH
• Cha ES

• KMID: 2392120
• DOI: http://doi.org/10.3348/jksr.2017.77.4.237

Abstract

Rhabdomyosarcoma mainly occurs in the pediatric age group, with the primary tumor originating from the trunk, neck, and extremities. Metastasis of rhabdomyosarcoma to the breast is very rare. Previous reports have suggested that the mammographic finding of breast rhabdomyosarcoma is an oval-shaped mass with irregular margins and the US finding is a solitary nodular lesion. We report a case of breast metastasis from pleural rhabdomyosarcoma in a 21-year-old woman, presenting as diffuse non-mass involvement and edematous change without a nodular mass.

MeSH Terms

Breast Neoplasms
Breast*
Extremities
Female
Humans
Neck
Neoplasm Metastasis*
Rhabdomyosarcoma*
Young Adult

Figure

• 

  Fig. 1 Breast metastasis from rhabdomyosarcoma in a 21-year-old female. A. Mammogram reveals global asymmetry (empty arrow) with diffuse skin thickening (arrowheads) in the right breast and several enlarged lymph nodes in the right axilla (white arrow). B, C. US reveals an ill-defined hypoechoic lesion (white arrow) with overlying skin thickening (black arrow) in the palpable site of the right breast. Increased vascularity around the lesion is demonstrated. D. There are a few enlarged lymph nodes with loss of fatty hilum in the right axilla. E. Microscopic section of the right breast mass. It shows diffuse growth pattern with small round cell composition. Tumor cells have hyperchromatic nuclei and abundant cytoplasm (arrowhead) (hematoxylin-eosin stain, × 400). F. Tumor cells immunostained for desmin shows a strong reaction (arrow).

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