Korean J Blood Transfus.  2017 Aug;28(2):103-112. 10.17945/kjbt.2017.28.2.103.

The Global Developments in Transfusion Replacements and Patient Blood Management

• Yang H
• Kim YW

• KMID: 2391227
• DOI: http://doi.org/10.17945/kjbt.2017.28.2.103

Abstract

Blood transfusions were once believed to the most potent and cost-effective method of improving patients' survival outcomes, but accumulating evidence over the past thirty years strongly suggests allogeneic transfusions as independent prognosticators of complications, prolonged hospital stay, and higher costs. A growing body of health care providers in Korea and throughout the world recognize a causal relationship between these adverse outcomes with liberal transfusion policies and call for a universal paradigm shift regarding the management of blood. Currently, the most promising contender is Patient Blood Management (PBM), which has been found to improve patient outcomes by conserving or optimizing the patient's own blood and physiologic reserves and advocating for restrictive transfusion policies. PBM incorporates evidence-based transfusion replacements to address anemia, bleeding, and blood disorders. These various methods-such as intravenous iron, erythropoiesis stimulating agents, coagulating factors, and topical hemostatic agents-are gaining recognition because of their ability to preclude the need for allogenic transfusions while effectively managing the patient's blood.

Keyword

Transfusion; Patient blood management; Transfusion replacement

MeSH Terms

Anemia
Blood Transfusion
Health Personnel
Hematinics
Hemorrhage
Humans
Iron
Korea
Length of Stay
Methods
Hematinics
Iron