Ann Hepatobiliary Pancreat Surg.  2017 Aug;21(3):146-150. 10.14701/ahbps.2017.21.3.146.

Safety of duodenal ampullectomy for benign periampullary tumors

• Kim AL
• Choi YI

• KMID: 2389991
• DOI: http://doi.org/10.14701/ahbps.2017.21.3.146

Abstract

BACKGROUNDS/AIMS
Surgical resection, such as pancreaticoduodenectomy (PD), is used for treatment of benign periampullary tumors, but high morbidity and mortality resulting from PD can be a huddle. The aim of this study is to suggest a safe and less invasive procedure for treatment of benign periampullary tumors.
METHODS
From January 2001 to September 2016, 31 patients with ampulla of Vater (AOV) tumors were reviewed retrospectively. Patients who were confirmed with malignancy through biopsy were excluded, except for one patient with malignancy and multiple underlying diseases. To investigate the safety and availability of transduodenal ampullectomy (TDA), TDA and endoscopic papillectomy (EP) were compared.
RESULTS
There was no significant difference in the occurrence of complications between the TDA group and EP group (p=0.145), and the resection margins were negative in both groups. There was no recurrence in patients who had TDA, while one patient had a recurrence after EP.
CONCLUSIONS
This study suggests that TDA is as safe as EP for treating benign periampullary tumors.

Keyword

Periampullary tumor; Transduodenal ampullectomy; Endoscopic papillectomy

MeSH Terms

Ampulla of Vater
Biopsy
Humans
Mortality
Pancreaticoduodenectomy
Recurrence
Retrospective Studies