Korean Circ J.  2016 Sep;46(5):601-609. 10.4070/kcj.2016.46.5.601.

J Wave Syndromes: History and Current Controversies

  • 1Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, The Second Hospital of Tianjin Medical University, Tianjin, China.
  • 2Department of cardiology, The Second Hospital of Jiaxing, Jiaxing, China.
  • 3Lankenau Institute for Medical Research and Lankenau Medical Center, Wynnewood, Pennsylvania, USA. YanG@mlhs.org
  • 4The First Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, China.


The concept of J wave syndromes was first proposed in 2004 by Yan et al for a spectrum of electrocardiographic (ECG) manifestations of prominent J waves that are associated with a potential to predispose affected individuals to ventricular fibrillation (VF). Although the concept of J wave syndromes is widely used and accepted, there has been tremendous debate over the definition of J wave, its ionic and cellular basis and arrhythmogenic mechanism. In this review article, we attempted to discuss the history from which the concept of J wave syndromes (JWS) is evolved and current controversies in JWS.


Brugada syndrome; Sudden cardiac death; Ventricular fibrillation

MeSH Terms

Brugada Syndrome
Death, Sudden, Cardiac
Ventricular Fibrillation
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