Korean Circ J.  2017 Sep;47(5):786-793. 10.4070/kcj.2017.0033.

How Long Can the Next Intervention Be Delayed after Balloon Dilatation of Homograft in the Pulmonary Position?

• Jeong HI
• Song J
• Choi EY
• Kim SH
• Huh J
• Kang IS
• Yang JH
• Jun TG

• KMID: 2389611
• DOI: http://doi.org/10.4070/kcj.2017.0033

Abstract

BACKGROUND AND OBJECTIVES
We investigated the effectiveness of balloon dilatation of homograft conduits in the pulmonary position in delaying surgical replacement.
SUBJECTS AND METHODS
We reviewed the medical records of patients who underwent balloon dilatation of their homograft in the pulmonary position from 2001 to 2015. The pressure gradient and ratio of right ventricular pressure were measured before and after the procedure. The primary goal of this study was to evaluate the parameters associated with the interval to next surgical or catheter intervention.
RESULTS
Twenty-eight balloon dilations were performed in 26 patients. The median ages of patients with homograft insertion and balloon dilatation were 20.3 months and 4.5 years, respectively. The origins of the homografts were the aorta (53.6%), pulmonary artery (32.1%), and femoral vein (14.3%). The median interval after conduit implantation was 26.7 months. The mean ratio of balloon to graft size was 0.87. The pressure gradient through the homograft and the ratio of right ventricle to aorta pressure were significantly improved after balloon dilatation (p<0.001). There were no adverse events during the procedure with the exception of one case of balloon rupture. The median interval to next intervention was 12.9 months. The median interval of freedom from re-intervention was 16.6 months. Cox proportional hazards analysis revealed that the interval of freedom from re-intervention differed only according to origin of the homograft (p=0.032), with the pulmonary artery having the longest interval of freedom from re-intervention (p=0.043).
CONCLUSION
Balloon dilatation of homografts in the pulmonary position can be safely performed, and homografts of the pulmonary artery are associated with a longer interval to re-intervention.

Keyword

Allografts; Angioplasty, balloon; Pulmonary valve stenosis; Re-intervention

MeSH Terms

Allografts*
Angioplasty, Balloon
Aorta
Catheters
Dilatation*
Femoral Vein
Freedom
Heart Ventricles
Humans
Medical Records
Pulmonary Artery
Pulmonary Valve Stenosis
Rupture
Transplants
Ventricular Pressure

Figure

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  Figure 1 Freedom from re-intervention after balloon dilatation of homografts.

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  Figure 2 Differences in freedom from re-intervention according to type of homograft; aorta, pulmonary artery and femoral vein.

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