Hip Pelvis.  2017 Sep;29(3):176-181. 10.5371/hp.2017.29.3.176.

Surgical Site Infection Following Fixation of Acetabular Fractures

Affiliations
  • 1Department of Orthopaedic Surgery, Liaquat National Hospital, Karachi, Pakistan. drfaizi1@yahoo.com

Abstract

PURPOSE
Acetabular fractures are mainly caused by high energy trauma. Surgical fixation of these fractures requires extensive surgical exposure which increases the length of operation and blood loss as well. This may increase the risk of surgical site infection. Our aim is to evaluate the prevalence of surgical site infections and the risk factors associated with it so as to minimize its chances.
MATERIALS AND METHODS
A total of 261 patients who underwent acetabular fracture surgery were retrospectively reviewed. Patients were divided into 2 groups, with or without surgical site infection. Factors examined include patients' gender, age, body mass index (BMI), time between injury and surgery, operative time, estimated blood loss, number of packed red blood cell transfused, length of total intensive care unit (ICU) stay, fracture type, surgical approach, smoking status, patients' comorbids and associated injuries.
RESULTS
Fourteen patients (5.4%) developed surgical site infection. Out of 14 infections, 4 were superficial and 10 were deep. The factors that were found to be associated with surgical site infection following acetabular fracture fixation were prolonged operation time, increased BMI, prolonged ICU stay, larger amount of packed red blood cell transfused and associated genitourinary and abdominal trauma.
CONCLUSION
In our study, we conclude that measures should be undertaken to attenuate the chances of surgical site infection in this major surgery by considering the risk factors significantly associated with it.

Keyword

Acetabular fractures; Surgical site infection; Risk factors

MeSH Terms

Acetabulum*
Body Mass Index
Erythrocytes
Fracture Fixation
Humans
Intensive Care Units
Operative Time
Prevalence
Retrospective Studies
Risk Factors
Smoke
Smoking
Surgical Wound Infection*
Smoke

Reference

1. Rao VS, Chandrasekhar P, Rao AL, Rao VB. Results of surgically treated displaced acetabular fractures among adults. Clin Proc NIMS. 2008; 17:2.
2. Olsen MA, Nepple JJ, Riew KD, et al. Risk factors for surgical site infection following orthopaedic spinal operations. J Bone Joint Surg Am. 2008; 90:62–69.
Article
3. Dinda V, Gunturu R, Kariuki S, Hakeem A, Raja A, Kimang’a A. Pattern of pathogens and their sensitivity isolated from surgical site infections at the Aga Khan University Hospital, Nairobi, Kenya. Ethiop J Health Sci. 2013; 23:141–149.
4. Letournel E. Acetabulum fractures: classification and management. Clin Orthop Relat Res. 1980; (151):81–106.
Article
5. Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. Guideline for prevention of surgical site infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. Am J Infect Control. 1999; 27:97–132. quiz 133-4; discussion 96.
6. Al-Mulhim FA, Baragbah MA, Sadat-Ali M, Alomran AS, Azam MQ. Prevalence of surgical site infection in orthopedic surgery: a 5-year analysis. Int Surg. 2014; 99:264–268.
Article
7. Suzuki T, Morgan SJ, Smith WR, Stahel PF, Gillani SA, Hak DJ. Postoperative surgical site infection following acetabular fracture fixation. Injury. 2010; 41:396–399.
Article
8. Mayo KA. Open reduction and internal fixation of fractures of the acetabulum. Results in 163 fractures. Clin Orthop Relat Res. 1994; (305):31–37.
Article
9. Peersman G, Laskin R, Davis J, Peterson MG, Richart T. Prolonged operative time correlates with increased infection rate after total knee arthroplasty. HSS J. 2006; 2:70–72.
Article
10. Cruse PJ, Foord R. The epidemiology of wound infection A 10-year prospective study of 62,939 wounds. Surg Clin North Am. 1980; 60:27–40.
Article
11. Pittet D, Tarara D, Wenzel RP. Nosocomial bloodstream infection in critically ill patients Excess length of stay, extra costs, and attributable mortality. JAMA. 1994; 271:1598–1601.
Article
12. Bernard AC, Davenport DL, Chang PK, Vaughan TB, Zwischenberger JB. Intraoperative transfusion of 1 U to 2 U packed red blood cells is associated with increased 30-day mortality, surgical-site infection, pneumonia, and sepsis in general surgery patients. J Am Coll Surg. 2009; 208:931–937. 931.e1–937.e2. discussion 938-9.
Article
13. Li Q, Liu P, Wang G, et al. Risk factors of surgical site infection after acetabular fracture surgery. Surg Infect (Larchmt). 2015; 16:577–582.
Article
14. Falagas ME, Kompoti M. Obesity and infection. Lancet Infect Dis. 2006; 6:438–446.
Article
15. Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med. 2009; 15:914–920.
Article
16. Canturk Z, Canturk NZ, Cetinarslan B, Utkan NZ, Tarkun I. Nosocomial infections and obesity in surgical patients. Obes Res. 2003; 11:769–775.
Article
17. Olsen MA, Mayfield J, Lauryssen C, et al. Risk factors for surgical site infection in spinal surgery. J Neurosurg. 2003; 98:2 Suppl. 149–155.
Article
18. Kaiser AB, Herrington JL Jr, Jacobs JK, Mulherin JL Jr, Roach AC, Sawyers JL. Cefoxitin versus erythromycin, neomycin, and cefazolin in colorectal operations Importance of the duration of the surgical procedure. Ann Surg. 1983; 198:525–530.
Article
19. Vamvakas EC, Carven JH. Transfusion of white-cell containing allogeneic blood components and postoperative wound infection: effect of confounding factors. Transfus Med. 1998; 8:29–36.
Article
20. Pealer LN, Marfin AA, Petersen LR, et al. Transmission of West Nile virus through blood transfusion in the United States in 2002. N Engl J Med. 2003; 349:1236–1245.
Article
21. Kurtz SM, Lau E, Watson H, Schmier JK, Parvizi J. Economic burden of periprosthetic joint infection in the United States. J Arthroplasty. 2012; 27:8 Suppl. 61–65.e1.
Article
22. Vegas AA, Jodra VM, Garcia ML. Nosocomial infection in surgery wards: a controlled study of increased duration of hospital stays and direct cost of hospitalization. Eur J Epidemiol. 1993; 9:504–510.
Article
23. Schaberg DR, Culver DH, Gaynes RP. Major trends in the microbial etiology of nosocomial infection. Am J Med. 1991; 91:72S–75S.
Article
24. Friedman G, Silva E, Vincent JL. Has the mortality of septic shock changed with time. Crit Care Med. 1998; 26:2078–2086.
Article
25. Richards MJ, Edwards JR, Culver DH, Gaynes RP. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol. 2000; 21:510–515.
Article
26. Nagachinta T, Stephens M, Reitz B, Polk BF. Risk factors for surgical-wound infection following cardiac surgery. J Infect Dis. 1987; 156:967–967.
Article
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