J Korean Acad Oral Health.  2017 Jun;41(2):110-115. 10.11149/jkaoh.2017.41.2.110.

A study on oral health-related quality of life following radiotherapy in patients with head and neck cancer

Affiliations
  • 1Department of Dentistry, Kyungpook National University Medical Center, Daegu, Korea.
  • 2Department of Dentistry, Yeungnam University College of Medicine, Daegu, Korea.
  • 3Department of Dental Hygiene, College of Science & Technology, Kyungpook National University, Sangju, Korea. jinha01@naver.com

Abstract


OBJECTIVES
The aim of this study was to assess the change in oral health-related quality of life among patients with head & neck cancer who received radiotherapy.
METHODS
A total of 40 patients who were diagnosed as having head and neck cancer and scheduled to have radiotherapy were enrolled in this study; however, only 25 patients were included in the final analysis. Prior to radiotherapy, a dentist performed an oral examination to check for the presence of decayed and missing teeth, plaque, and determine the gingival index. Oral health-related quality of life was assessed using the OHIP-14 questionnaire. Eight weeks after starting radiotherapy, oral health-related quality of life was re-evaluated using the same questionnaire.
RESULTS
The mean age of the participants was 60.20 (±7.29) years, and 22 (88.8%) of them were men. The majority of the participants were diagnosed as having squamous cell carcinoma (68.0%). The total OHIP-14 score was significantly decreased from 56.20 (±13.50) at baseline to 45.72 (±10.98) eight weeks after radiotherapy. In addition, according to subjective oral health at baseline, the observed change in the OHIP-14 score was significantly different.
CONCLUSIONS
Oral health-related quality of life was significantly lowered after radiotherapy in patients with head and neck cancer.

Keyword

Head & Neck Cancer; Oral Health Related Quality of Life; Radiotherapy

MeSH Terms

Carcinoma, Squamous Cell
Dentists
Diagnosis, Oral
Head and Neck Neoplasms*
Head*
Humans
Male
Oral Health
Periodontal Index
Quality of Life*
Radiotherapy*
Tooth

Cited by  1 articles

Effect of apoptosis on G361 cells by Cimicifuga rhizoma extract
Byul Bo Ra Choi, Gyoo Cheon Kim, Jin Woo Hong, Sang Rye Park
J Korean Acad Oral Health. 2019;43(2):72-77.    doi: 10.11149/jkaoh.2019.43.2.72.


Reference

1. Hopkins J, Cescon DW, Tse D, Bradbury P, Xu W, Ma C, et al. Genetic polymorphisms and head and neck cancer outcomes: a review. Cancer Epidemiol Biomarkers Prev. 2008; 17(3):490–499.
Article
2. Kim MS. The role of head and neck surgeon as oncologist in head and neck cancer. J Clin Oncol. 2008; 4:33–36.
Article
3. Browman GP, Hodson DI, Mackenzie RJ, Bestic N, Zuraw L. Choosing a concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: a systematic review of the published literature with subgroup analysis. Head Neck. 2001; 23(7):579–589.
Article
4. Vissink A, Jansma J, Spijkervet FKL, Burlage FR, Coppes RP. Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med. 2003; 14(3):199–212.
Article
5. Trotti A, Bellm LA, Epstein JB, Frame D, Fuchs HJ, Gwede CK, et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: a systematic literature review. Radiother Oncol. 2003; 66(3):253–262.
Article
6. Scully C, Epstein J, Sonis S. Oral mucositis: a challenging complication of radiotherapy, chemotherapy, and radiochemotherapy: part 1, pathogenesis and prophylaxis of mucositis. Head Neck. 2003; 25(12):1057–1070.
Article
7. Park Y, Kim YH. Chemotherapy related oral and gastrointestinal mucositis. J Korean Med Assoc. 2009; 52(9):897–906.
Article
8. Choi SE, Kim HS. Reliability and validity of patient self-reported daily questionnaire on oral Mucositis in acute leukemic patients under chemotherapy. J Korean Biol Nurs Sci. 2010; 12(3):148–156.
9. McMillan AS, Pow EHN, Leung WK, Wong MCM, Kwong DLW. Oral health-related quality of life in southern Chinese following radiotherapy for nasopharyngeal carcinoma. J Oral Rehabil. 2004; 31(6):600–608.
Article
10. Kwon YE, Kim YK, Bae KH, Jin BH, Kim HD, Paik DI. The relationship between compliance with self-fluoride gel application and oral health-related quality of Life in patients undergoing irradiated irradiation patients for head and neck cancer therapy. J Korean Acad Dent Health. 2009; 33(2):153–163.
11. Loe H. The gingival index, the plaque index and the retention index systems. J Periodontol. 1967; 38:Suppl610–616.
12. Bae KH, Kim HD, Jung SH, Park DY, Kim JB, Paik DI, et al. Validation of the Korean version of the oral health impact profile among the Korean elderly. Community Dent Oral Epidemiol. 2007; 35(1):73–79.
Article
13. Ramaekers BL, Joore MA, Grutters JP, Van Den Ende P, De Jong J, Houben R, et al. The impact of late treatment-toxicity on generic health-related quality of life in head and neck cancer patients after radiotherapy. Oral Oncol. 2011; 47(8):768–774.
Article
14. Sciubba JJ, Goldenberg D. Oral complications of radiotherapy. Lancet Oncol. 2006; 7(2):175–183.
Article
15. de Leeuw JR, de Graeff A, Ros WJ, Blijham GH, Hordijk GJ, Winnubst JA. Prediction of depression 6 months to 3 years after treatment of head and neck cancer. Head Neck. 2001; 23(10):892–898.
Article
Full Text Links
  • JKAOH
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr