Ann Dermatol.  2017 Oct;29(5):653-654. 10.5021/ad.2017.29.5.653.

A Case of Subungual Melanoma In Situ in an 18-Year-Old Girl Presented with Total Melanonychia

• Woo CH
• Ham SP
• Choi M
• Park HJ

• KMID: 2388928
• DOI: http://doi.org/10.5021/ad.2017.29.5.653

Abstract

No abstract available.

MeSH Terms

Adolescent*
Female*
Humans
Melanoma*

Figure

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  Fig. 1 The patient presentsd with total melanonychia with splitting and fissuring of the nail plate on the right thumbnail. Hutchinson's sign was indicated on the proximal and lateral nail folds.

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  Fig. 2 (A) Proliferation of atypical melanocyte with pagetoid spread were noted in the nail bed (H&E, ×200). (B) Biopsy specimen of the fingertip demonstrated lentiginous proliferation of hyperchromatic, pleomorphic melanocytes at the dermal-epidermal junction and pagetoid spreading in the epidermis. No dermal invasion was noted (H&E, ×200). (C) HMB-45 stain reveals atypical melanocytes with pagetoid spread in the nail bed (immunoperoxidase, ×200).

Reference

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