Prog Med Phys.  2017 Jun;28(2):39-44. 10.14316/pmp.2017.28.2.39.

Evaluation of Dosimetric Effect and Treatment Time by Plan Parameters for Endobronchial Brachytherapy

• Choi CH
• Park JM
• Park SY
• Kang S
• Cho JD
• Kim JI

• KMID: 2388206
• DOI: http://doi.org/10.14316/pmp.2017.28.2.39

Abstract

This study aims to analyze dose distribution and treatment time of endobronchial brachytherapy (EBBT) by changing the position step size of the dwell position. A solid water phantom and an intraluminal catheter were used in the treatment plan. The treatment plans were generated for 3, 5, 7, and 10 cm treatment lengths, respectively. For each treatment length, the source position step sizes were set as 2.5, 5, and 10 mm. Three reference points were set 1 cm away from the central axis of the catheter, along the axis, for uniform dose distribution. Volumetric dose distribution was calculated to evaluate the dosimetric effect. The total radiation delivery time and total dwell time were estimated for treatment efficiency, which were increased with position step sizes. At half-life time, the differences between the position step sizes in the total radiation delivery time were 18.1, 15.4, 18.0, and 24.0 s for 3, 5, 7, and 10 cm treatment lengths, respectively. The dose distributions were more homogenous by increasing the position step sizes. The dose difference of the reference point was less than 10%. In brachytherapy, this difference can be negligible. For EBBT, the treatment time is the key factor while considering the patient status. To reduce the total treatment time, EBBT can be performed with 2.5 mm position step size.

Keyword

Endobronchial; Brachytherapy; Treatment planning; Position step size

MeSH Terms

Brachytherapy*
Catheters
Half-Life
Humans
Water
Water

Figure

• 

  Fig. 1. Dose distribution in coronal view for each position step size and treatment length. (a-1): Position step size=2.5 mm, treatment length=3 cm; (a-2): position step size=5 mm, treatment length=3 cm; (a-3): position step size=10 mm, treatment length=3 cm; (b-1): position step size=2.5 mm, treatment length=5 cm; (b-2): position step size=5 mm, treatment length=5 cm; (b-3): position step size=10 mm, treatment length=5 cm; (c1): position step size=2.5 mm, treatment length=7 cm; (c-2): position step size=5 mm, treatment length=7 cm; (c-3): position step size=10 mm, treatment length=7 cm; (d-1): position step size=2.5 mm, treatment length=10 cm; (d-2): position step size=5 mm, treatment length=10 cm; (d-3): position step size=10 mm, treatment length=10 cm.

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