Nat Prod Sci.  2017 Jun;23(2):146-150. 10.20307/nps.2017.23.2.146.

Quantitative Analysis and Validation of Hirsutenone and Muricarpone B from Fermented Alnus sibirica

• YIN J
• YOON KH
• YOON SH
• AHN HS
• LEE MW

• KMID: 2387066
• DOI: http://doi.org/10.20307/nps.2017.23.2.146

Abstract

Alnus sibirica (AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of this plant had been used for antipyretic, expectorant, anti-phlogistic, antitussive, anti-asthmatic and as a health tea for alcoholism. Recently, we studied various biological activities of AS and the isolated diarylheptanoid. In present study, we conducted fermentation of AS (FAS) and isolated two diarylheptanoid (hirsutenone and muricarpone B). Moreover, we established the validation and contents determinations of the two compounds by HPLC on FAS.

Keyword

Alnus sibirica; Fermentation; HPLC; Validation; Content

MeSH Terms

Alcoholism
Alnus*
China
Chromatography, High Pressure Liquid
Fermentation
Japan
Korea
Plants
Russia
Tea
Tea

Figure

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  Fig. 1. The structures of main components of FAS, oregonin, hirsutenone and muricarpone B.

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  Fig. 2. HPLC pattern of FAS, AS and the specificity of hirsutenone and muricarpone B.

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  Fig. 3. Linearity of hirsutenone.

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  Fig. 4. Linearity of muricarpone B.

Reference

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