Soonchunhyang Med Sci.  2016 Dec;22(2):115-118. 10.0000/sms.2016.22.2.115.

Biocidal Effect of Hypochlorous Acid Solution, Neolox against Pathogenic Microorganisms

• Bang HI
• Choi TY

• KMID: 2387002
• DOI: http://doi.org/10.0000/sms.2016.22.2.115

Abstract

OBJECTIVE
Disinfection/sterilization of hospital devices prevents the occurrence of several infections; therefore, disinfectants are essential for public health. The purpose of this study was to evaluate the biocidal effect of a hypochlorous acid solution.
METHODS
Hypochlorous acid solution, Neolox (Neo Chemical, Paju, Korea) obtained from Purester (Morinaga Engineering, Tokyo, Japan) was used. Antimicrobial activity of the solution against bacteria, yeasts, and mycobacteria at different exposure times (0.5, 1, 2, 5, 10, 15, and 30 minutes) was evaluated.
RESULTS
All strains of bacteria and yeasts showed a 5-log10 reduction within 30 seconds of exposure to the solution, and mycobacteria showed the same reduction within 2 minutes.
CONCLUSION
Hypochlorous acid solution has been widely used as a disinfectant in recent years. Neolox can be used as an effective intermediate- to high-level disinfectant for hospital infection control.

Keyword

Hypochlorous acid; Disinfectants; Infection

MeSH Terms

Bacteria
Cross Infection
Disinfectants
Hypochlorous Acid*
Public Health
Yeasts
Disinfectants
Hypochlorous Acid