J Korean Soc Emerg Med.  2017 Jun;28(3):231-239. 10.0000/jksem.2017.28.3.231.

The Utility of Measuring the Difference between the Two Optic Nerve Sheath Diameters Using Ultrasonography in Predicting Operation Indication in Patients with Traumatic Brain Hemorrhage

• Park CJ
• Sun KH
• Cho SH
• Kim SJ

• KMID: 2386574
• DOI: http://doi.org/10.0000/jksem.2017.28.3.231

Abstract

PURPOSE
An increase in optic nerve sheath diameter (ONSD) has been associated with elevated intracranial pressure due to brain lesions, such as hemorrhage, infarction, and tumor. The aim of this study was to evaluate whether the difference of both ONSDs can predict surgical treatment in patients with traumatic brain hemorrhage.
METHODS
A prospective analysis of the data acquired between September 2016 and November 2016 was performed. We included 155 patients with traumatic brain hemorrhage undergoing computed tomography in the emergency room. We performed an ultrasonography to measure ONSDs for all included patients. The primary outcome of this study was operation indication in patients with traumatic brain hemorrhage.
RESULTS
The average age was 63.4±17.0 years (male 60.3±17.3, female 69.8±14.4). There were 61 (39.35%) patients with an indication for operation and 94 (60.65%) patients with an indication for no operation. Indications for operation showed a strong association with the difference of both ONSDs in patients with subdural hemorrhage (p<0.001), no association between them in patients with epidural and intracerebral hemorrhage. In patients with subdural hemorrhage, the area under the curve was 0.988 (0.653-0.998), and the cut-off value for the difference of ONSDs with respect to determining the indications for operation was 0.295 mm f maximizing the sum of the sensitivity (96.9%) and specificity (90.7%) using the receiver operating curve.
CONCLUSION
A difference of both ONSDs above 0.295 mm was useful in predicting the indications for operation in patients with traumatic subdural hemorrhage, but not in patients with epidural and intracerebral hemorrhage.

Keyword

Optic nerve; Ultrasonography; Hematoma; subdural; Hematoma; epidural; cranial; Cerebral hemorrhage

MeSH Terms

Brain
Brain Hemorrhage, Traumatic*
Cerebral Hemorrhage
Emergency Service, Hospital
Female
Hematoma, Subdural
Hemorrhage
Humans
Infarction
Intracranial Hypertension
Optic Nerve*
Prospective Studies
Sensitivity and Specificity
Ultrasonography*