Infect Chemother.  2017 Jun;49(2):130-134. 10.3947/ic.2017.49.2.130.

Is the Initial Size of Tuberculous Lymphadenopathy associated with Lymph Node Enlargement during Treatment?

Affiliations
  • 1Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Korea. ktocc2@naver.com
  • 2Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul Korea.
  • 3Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.

Abstract

There are little data on the changes in lymph node (LN) size during the treatment of tuberculous lymphadenopathy (TB LAP). This study aimed to provide data on LN changes during treatment. Between March 2014 and December 2015, 20 patients who were diagnosed with cervical TB LAP were enrolled. LN enlargement within two months (50%, 4/8 vs. 8.3%, 1/12; P = 0.04) was more frequently observed in patients with initial LN size ≥ 7.5 cm². Enlarged LNs were excised in three patients owing to pain and fistula formation. Initial LN size may be associated with LN enlargement during treatment.

Keyword

Tuberculosis; Lymphadenopathy; Outcome

MeSH Terms

Fistula
Humans
Lymph Nodes*
Lymphatic Diseases*
Tuberculosis

Figure

  • Figure 1 Treatment outcomes of tuberculous lymphadenopathy according to initial lymph node size. Five (25%) patients received LN excision for the following reasons: athree for complaints associated with pain and fistula, bone due to a request for remaining LN excision, and cone for diagnostic purposes. LN enlargement during treatment was more frequently observed in patients with initial LN size ≥ 7.5 cm2, compared to those < 7.5 cm2 (50%, 4/8 vs. 8.3%, 1/12; P = 0.04). LN, lymph node.


Cited by  1 articles

Clinical Course of Patients With Mediastinal Lymph Node Tuberculosis and Risk Factors for Paradoxical Responses
Junsu Choe, Areum Han, Sun Hye Shin, Kyungjong Lee, Sang-Won Um, Hojoong Kim, Tae Yeul Kim, Hee Jae Huh, Yoon-La Choi, Joungho Han, Byeong-Ho Jeong
J Korean Med Sci. 2023;38(47):e348.    doi: 10.3346/jkms.2023.38.e348.


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