J Korean Soc Surg Hand.  2017 Jun;22(2):127-131. 10.12790/jkssh.2017.22.2.127.

Subungual Extraskeletal Chondroma with Nail Deformity

• Ahn KB
• Rhyou IH
• Kim KC
• Kim SZ

• KMID: 2383806
• DOI: http://doi.org/10.12790/jkssh.2017.22.2.127

Abstract

Extraskeletal chondromas are benign soft tissue tumor of hyaline cartilage. These tumors are rare and the pathogenesis is unclear. They are usually involves the hand or feet. We report the case of extraskeletal chondroma arising from subungual region of the finger with nail deformity and review of the literature.

Keyword

Chondroma; Finger

MeSH Terms

Chondroma*
Congenital Abnormalities*
Fingers
Foot
Hand
Hyaline Cartilage

Figure

• 

  Fig. 1 Clinical photograph of the right fifth finger. A mass lesion can be seen arising from lunula. Nail deformity and discoloration in nail plate observed.

• 

  Fig. 2 Anteroposterior radiographs of both hands. The distal phalanx deformation of the right fifth finger observed

• 

  Fig. 3 T1-weighted sagittal image revealed a well-demarcated mass in subungual region with low signal intensity.

• 

  Fig. 4 After total nail extracted, white and firm mass showed without connection to underlying bone.

• 

  Fig. 5 Low power photomicrograph shows a well-demarcated mass with lobules of abundant hyaline cartilage matrix (Hematoxylin and Eosin stain, ×40).

• 

  Fig. 6 On high power section, the hypercellular hyaline cartilage is composed of chondrocytes which have uniform small round nuclei and finely granular, eosinophilic cytoplasm. Binucleation and slight cellular atypia of chondrocytes are focally seen (Hematoxylin and Eosin stain, ×200).

Reference

1. Chung EB, Enzinger FM. Chondroma of soft parts. Cancer. 1978; 41:1414–1424.

2. Adaletli I, Laor T, Yin H, Podberesky DJ. Extraskeletal chondroma: another diagnostic possibility for a soft tissue axillary mass in an adolescent. Case Rep Orthop. 2011; 2011:309328.

3. Ishii T, Ikeda M, Oka Y. Subungual extraskeletal chondroma with finger nail deformity: case report. J Hand Surg Am. 2010; 35:296–299.

4. Eun YS, Kim MR, Cho BK, Yoo G, Park HJ. Subungual soft tissue chondroma with nail deformity in a child. Pediatr Dermatol. 2015; 32:132–134.

5. Zlatkin MB, Lander PH, Begin LR, Hadjipavlou A. Soft-tissue chondromas. AJR Am J Roentgenol. 1985; 144:1263–1267.

6. De Riu G, Meloni SM, Gobbi R, Contini M, Tullio A. Soft-tissue chondroma of the masticatory space. Int J Oral Maxillofac Surg. 2007; 36:174–176.

7. Han JY, Han HS, Kim YB, Kim JM, Chu YC. Extraskeletal chondroma of the fallopian tube. J Korean Med Sci. 2002; 17:276–278.

8. Ammor R, Ajja A. Chondroma of the scalp. Pan Afr Med J. 2015; 21:64.

9. Kransdorf MJ, Meis JM. From the archives of the AFIP: extraskeletal osseous and cartilaginous tumors of the extremities. Radiographics. 1993; 13:853–884.

10. Scotlandi K, Serra M, Manara MC, et al. Clinical relevance of Ki-67 expression in bone tumors. Cancer. 1995; 75:806–814.