Ann Dermatol.  1999 Oct;11(4):267-270. 10.5021/ad.1999.11.4.267.

A Case of Cutaneous Metastasis from Esophageal Carcinoma

Abstract

We report a case of cutaneous metastatic carcinoma from an esophageal carcinoma in a 54-year-old male who complained of several pinhead-sized erythematous tender papules on the up-per chest. He had been admitted to the department of internal medicine for esophageal carcinoma. Radiological examinations revealed a luminal narrowing below the level of carina on esophagography, and a mass on the mid esophagus, left atrium and pulmonary vein on the chest CT scan. On endoscopy, about 30cm from the central incisor, a huge polypoid mass with a central ulceration and dirty surface margin was noted. Histopathological examination of the skin and esophageal biopsies showed the same atypical squamous cells with distinctive nucleoli, nuclear membrane and intercellular bridge, which were consistent with the squamous cell carcinoma of nonkeratinizing large cell type, suggesting these cutaneous lesions were metastasized from the esophageal carcinoma.

Keyword

Cutaneous metastasis; Esophageal carcinoma

MeSH Terms

Atypical Squamous Cells of the Cervix
Biopsy
Carcinoma, Squamous Cell
Endoscopy
Esophagus
Heart Atria
Humans
Incisor
Internal Medicine
Male
Middle Aged
Neoplasm Metastasis*
Nuclear Envelope
Phenobarbital
Pulmonary Veins
Skin
Thorax
Tomography, X-Ray Computed
Ulcer
Phenobarbital
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