Korean J Thorac Cardiovasc Surg.  2015 Dec;48(6):422-425. 10.5090/kjtcs.2015.48.6.422.

Isolated Tricuspid Regurgitation: Initial Manifestation of Cardiac Amyloidosis

• Yoon DW
• Park BJ
• Kim IS
• Jeong DS

• KMID: 2382302
• DOI: http://doi.org/10.5090/kjtcs.2015.48.6.422

Abstract

Amyloid deposits in the heart are not exceptional in systemic amyloidosis. The clinical manifestations of cardiac amyloidosis may include restrictive cardiomyopathy, characterized by progressive diastolic and eventually systolic bi-ventricular dysfunction; arrhythmia; and conduction defects. To the best of our knowledge, no previous cases of isolated tricuspid regurgitation as the initial manifestation of cardiac amyloidosis have been reported. We describe a rare case of cardiac amyloidosis that initially presented with severe tricuspid regurgitation in a 42-year-old woman who was successfully treated with tricuspid valve replacement. Unusual surgical findings prompted additional evaluation that established a diagnosis of plasma cell myeloma.

Keyword

Tricuspid valve; Amyloidosis

MeSH Terms

Adult
Amyloidosis*
Arrhythmias, Cardiac
Cardiomyopathy, Restrictive
Diagnosis
Female
Heart
Humans
Multiple Myeloma
Plaque, Amyloid
Tricuspid Valve
Tricuspid Valve Insufficiency*