Korean J Parasitol.  2015 Jun;53(3):329-333. 10.3347/kjp.2015.53.3.329.

A Rare Human Case of Dirofilaria repens Infection in the Subcutaneous Posterior Thorax with Molecular Identification

Affiliations
  • 1Department of Parasitology, Vietnam Military Medical University, Hanoi, Vietnam.
  • 2Department of Pathology, Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam.
  • 3Immunology Department, Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. imibtvn@gmail.com

Abstract

The emergence of Dirofilarial infections in Asia including Vietnam is a clinically significant threat to the community. We here report a rare case of subcutaneous Dirofilaria repens infection on the posterior thoracic wall in a young woman presenting a painful, itchy, and palpable nodule. The adult worm was identified by mitochondrial cox1 and nuclear ITS-2 sequence determination. The diagnosis was additionally confirmed by 16S rRNA sequencing of the endosymbiont Wolbachia pipientis commonly co-existing with D. repens. This is a rare case of subcutaneous human infection on the posterior thoracic region caused by D. repens.

Keyword

Dirofilaria repens; subcutaneous Dirofilariasis; molecular identification

MeSH Terms

Adult
Animals
Dirofilaria repens/classification/genetics/*isolation & purification/physiology
Dirofilariasis/diagnosis/*parasitology
Female
Humans
Phylogeny
Thorax/*parasitology
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