J Pathol Transl Med.  2015 May;49(3):274-278. 10.4132/jptm.2015.03.12.

A Case of Primary Subpleural Pulmonary Microcystic Myxoma Coincidentally Occurred with Pulmonary Adenocarcinoma

• Ahn J
• Kim NR
• Ha SY
• Kim KW
• Park KY
• Sung YM

• KMID: 2381389
• DOI: http://doi.org/10.4132/jptm.2015.03.12

Abstract

No abstract available.

MeSH Terms

Adenocarcinoma*
Myxoma*

Figure

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  Fig. 1. (A) Precontrast chest computed tomography shows a well-delineated low-attenuated oval mass (arrow) with slightly high density delete the portion in the subpleural area. (B) Gross photo shows a well-demarcated ovoid mass (arrow) with a mucous gelatinous texture with focal hemorrhage.

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  Fig. 2. (A–C) Touch imprint cytology. (A) Hypocellular smear shows many scattered inflammatory cells and macrophages. Note the background amorphous mucin-like metachromatic materials. (B) High-power view shows round to spindle cells having a moderate amount of granular cytoplasm and euchromatic round nuclei. (C) Note rare intranuclear inclusions (left, arrow) and cytoplasmic globular materials (right, arrow) (A–C, Papanicolaou stain). (D–F) Histologic findings. (D) Low-power view shows a well-demarcated bluish mass, and the mass is composed of predominantly chondromyxoid stroma. Arrow indicates normal pulmonary parenchyma. (E) High-power view shows that the mass is composed of abundant bluish chondromyxoid stroma and the paucicellular elements including scattered spindle cells, intermixed macrophages, mature lymphocytes, and some eosinophils. (F) Microcysts are surrounded by attenuated flattened cells or no lining (left, H&E stain; right, Vimentin immunostain).

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  Fig. 3. Ultrastructural examination reveals spindle to round cells with round euchromatic nuclei and cytoplasm having many lysosomes, mitochondria, and rough endoplasmic reticulums. Extracellular amorphous mucin material (arrow) is observed (left, ×2,500). Multiple ruffled cell surfaces (thin arrow) and abundant collagen fibrils (thick arrow) are also observed (right, ×3,500).

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