J Pathol Transl Med.  2015 Jan;49(1):81-84. 10.4132/jptm.2014.06.03.

Alveolar Rhabdomyosarcoma of the Lip in an Adult with Clear Cell Features

• Seok JY
• Jeong J
• Cheon YW
• Cho HY
• Ha SY
• Chung DH

• KMID: 2381359
• DOI: http://doi.org/10.4132/jptm.2014.06.03

Abstract

No abstract available.

MeSH Terms

Adult*
Humans
Lip*
Rhabdomyosarcoma, Alveolar*

Figure

• 

  Fig. 1. (A) A skin-colored nodule is noted in the upper lip (arrow). (B) An ill-defined mass involves the dermis and subcutaneous fat tissue. (C) The tumor cells extend to the papillary dermis but do not invade the epidermis. (D) The tumor is composed of densely packed groups of small round cells intersecting collagen bundles with marked clear cell change and frequent mitotic figures (arrow).

• 

  Fig. 2. (A) Periodic acid–Schiff stain shows a few glycogen particles in the cytoplasm (arrow). (B) The cytoplasm is intensively immunoreactive for desmin, and a tumor cell shows striation-like features in the cytoplasm (asterisk). (C) The nuclei are positive for myogenin immunohistochemical stain. (D) Ultrastructurally, the tumor cell shows intracytoplasmic filaments (arrow) (×60,000).

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