Clin Pediatr Hematol Oncol.  2017 Apr;24(1):37-42. 10.15264/cpho.2017.24.1.37.

Gonadal Function in Female Childhood Cancer Survivors

Affiliations
  • 1Department of Pediatrics, Gyeongsang National University Changwon Hospital, Changwon, Korea.
  • 2Department of Pediatrics, College of Medicine, Gyeongsang National University, Jinju, Korea. espark@gnu.ac.kr
  • 3Gyeongsang Institute of Health Science, Gyeongsang National University, Jinju, Korea.

Abstract

During the last three decades childhood cancer survivorship study has extensively developed and now we have much extent of knowledge about survivor's long-term mortality and chronic illness. One of the many challenges that females survivors face includes reproductive health, which involves reproductive and sexual health changes that could later significantly reduce one's quality of life. Alkylating chemotherapy, irradiation of the CNS and/or ovaries, and pelvic and genitourinary surgery can adversely affect the reproductive organs. Increased awareness of the unique needs of female cancer survivors, timely evaluation of gonadal function, and active intervention for fertility preservation before, during, and after therapy is warranted.

Keyword

Female; Childhood; Neoplasm; Survivors; Hypogonadism; Infertility

MeSH Terms

Chronic Disease
Drug Therapy
Female*
Fertility Preservation
Gonads*
Humans
Hypogonadism
Infertility
Mortality
Ovary
Quality of Life
Reproductive Health
Survival Rate
Survivors*
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