Obstet Gynecol Sci.  2017 May;60(3):308-313. 10.5468/ogs.2017.60.3.308.

Hyperthermic intrathoracic chemotherapy with cisplatin for ovarian cancer with pleural metastasis

Affiliations
  • 1Department of Obstetrics and Gynecology, Kyungpook National University Medical Center, Daegu, Korea. dghong@knu.ac.kr
  • 2Department of Thoracic and Cardiovascular Surgery, Kyungpook National University Medical Center, Daegu, Korea.
  • 3Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan.

Abstract

Intrathoracic metastasis of ovarian cancer has poor prognosis regardless of treatment modality. Recent development of surgical techniques and the new concept of direct infusion of chemotherapeutic agents with hyperthermia could help with the treatment of disseminated diseases in ovarian cancer. Using video-assisted thoracoscopic surgery and intracavitary chemotherapy with hyperthermia, we tried hyperthermic intrathoracic chemotherapy for a case of stage IV high-grade serous ovarian cancer with pleural metastasis. There was no high-grade complication related to the procedure. The patient is alive without disease at 32 months after initial treatment.

Keyword

Drug therapy; Fever; Neoplasm metastasis; Ovarian neoplasms

MeSH Terms

Cisplatin*
Drug Therapy*
Fever
Humans
Neoplasm Metastasis*
Ovarian Neoplasms*
Prognosis
Thoracic Surgery, Video-Assisted
Cisplatin
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