J Korean Soc Traumatol.  2016 Dec;29(4):124-128. 10.20408/jti.2016.29.4.124.

The Risk Factors for Developing Contrast-induced Nephropathy after the Evaluation of Trauma Patients at a Regional Trauma Center in Korea

• An YM
• Park SC
• Kim HB
• Cho YM
• Lee DS
• Kim YI
• Han SK

• KMID: 2378445
• DOI: http://doi.org/10.20408/jti.2016.29.4.124

Abstract

PURPOSE
Computed tomography (CT) with intravenous (IV) contrast is an important step in the evaluation of trauma patients; however, the risk factors for contrast-induced nephropathy (CIN) in these patients remain unclear. This study determined the rate of CIN in trauma patients at a regional trauma center in Korea and identified the risk factors for developing CIN.
METHODS
We retrospectively reviewed the medical records of 138 patients for the patient demographics, creatinine levels, and vital signs. CIN was defined as an increase in creatinine by 0.5 mg/dL from admission after undergoing CT with IV contrast.
RESULTS
Of the patients, 7.2% developed CIN during their admission after receiving IV contrast for CT. In the multivariate analysis, only the creatinine level at presentation (Adjusted odds ratio [aOR], 5.944; 95% confidence interval [CI], 1.486-23.733; p=0.012) and an injury severity score (ISS) greater than 22 (aOR, 1.096; 95% CI, 1.021-1.176; p=0.011) were independently associated with the risk of CIN.
CONCLUSION
CIN is uncommon in trauma patients following CT with IV contrast. The creatinine level at presentation and ISS were independent risk factors for developing CIN in trauma patients.

Keyword

Contrast-induced nephropathy; Contrast medium

MeSH Terms

Creatinine
Demography
Humans
Injury Severity Score
Korea*
Medical Records
Multivariate Analysis
Odds Ratio
Retrospective Studies
Risk Factors*
Trauma Centers*
Vital Signs
Creatinine