Urogenit Tract Infect.  2017 Apr;12(1):35-41. 10.14777/uti.2017.12.1.35.

The Effects of Microwave Thermotherapy for Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Prospective, Randomized Study

• Chung H
• Choi H
• Yoo TK
• Cho JM
• Kim HS

• KMID: 2378147
• DOI: http://doi.org/10.14777/uti.2017.12.1.35

Abstract

PURPOSE
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) causes pain and urinary symptoms that involve the prostate and/or other parts of the male. We analyzed the clinical outcomes of medication and microwave thermotherapy.
MATERIALS AND METHODS
A total of 132 patients with CP/CPPS for at least 3 months were assigned to one of the three study groups (group A: medication; group B: thermotherapy; group C: combination therapy). The NIH-CPSI was recorded at baseline, and at weeks 2, 4, 8, and 12 post-therapy. EPS was evaluated, and semen analysis was performed to assess the changes in prostatic inflammation. Moreover, patient satisfaction questionnaire was completed.
RESULTS
Comparisons between groups A and B, as well as between groups B and C showed no significant changes in pain, quality of life, and total scores. At week 12, group C, when compared with group A, had a significantly improved voiding score (4.19±3.02 vs. 2.71±2.30, p=0.019) and EPS (12.47±15.91 vs. 3.73±4.82, p=0.003). At week 4, the patient satisfaction score in group C was significantly different from that in other groups (p=0.043), but there was no difference at week 12 (p>0.05). There was no statistically significant difference in laboratory test results, PSA, and prostate volume between the three groups at baseline and week 12. Complications of thermotherapy resolved with conservative management.
CONCLUSIONS
Our results showed that a combination of medication and thermotherapy improved NIH-CPSI and patient satisfaction in CP/CPPS more than medication alone. We suggested that thermotherapy could be another treatment option for CP/CPPS.

Keyword

Drug therapy; Microwaves; Prostate; Prostatitis

MeSH Terms

Drug Therapy
Humans
Hyperthermia, Induced*
Inflammation
Male
Microwaves*
Patient Satisfaction
Pelvic Pain*
Prospective Studies*
Prostate
Prostatitis
Quality of Life
Semen Analysis

Figure

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  Fig. 1. URO-DRTM (Somang Medical, Gangneung, Korea).

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  Fig. 2. Study flow diagram. Group A: medical therapy, group B: microwave thermotherapy, group C: medication and microwave thermotherapy.

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  Fig. 3. Changes of pain, voiding, quality of life (QoL), and total score. Group A: medical therapy, group B: microwave thermotherapy, group C: medication and microwave thermotherapy, NIH-CPSI: The National Institutes of Health Chronic Prostatitis Symptom Index.

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