J Periodontal Implant Sci.  2017 Apr;47(2):96-105. 10.5051/jpis.2017.47.2.96.

Association between periodontal flap surgery for periodontitis and vasculogenic erectile dysfunction in Koreans

• Lee JH
• Choi JK
• Kim SH
• Cho KH
• Kim YT
• Choi SH
• Jung UW

• KMID: 2377744
• DOI: http://doi.org/10.5051/jpis.2017.47.2.96

Abstract

PURPOSE
The National Health Insurance Service-National Sample Cohort and medical checkup data from 2002 to 2013 were used to evaluate the association between periodontal surgery for the treatment of periodontitis (PSTP) and vasculogenic erectile dysfunction (VED).
METHODS
Bivariate and multivariate logistic regression analyses were applied to a longitudinal retrospective database to assess the association between PSTP and VED while adjusting for the potential confounding effects of sociodemographic factors (age, household income, insurance status, health status, residence area, and smoking status) and comorbidities (diabetes mellitus, angina pectoris, cerebral infarction, and myocardial infarction).
RESULTS
Among the 7,148 PSTP within the 268,296 recruited subjects, the overall prevalence of VED in PSTP was 1.43% (n=102). The bivariate analysis showed that VED was significantly related to PSTP (odds ratio [OR], 1.99; 95% confidence interval [CI], 1.38-2.06; P<0.001), and this was confirmed in the multivariate analysis after adjusting for sociodemographic factors and comorbidities (OR, 1.29; 95% CI, 1.06-1.58; P=0.002).
CONCLUSIONS
Subjects with a history of periodontal flap surgery had a significantly higher risk of VED, after adjusting for potential confounding factors. Further studies are required to identify the key mechanisms underlying the association between severe periodontal disease and VED.

Keyword

Chronic periodontitis; Cohort studies; Erectile dysfunction; Periodontal diseases; Retrospective studies

MeSH Terms

Angina Pectoris
Cerebral Infarction
Chronic Periodontitis
Cohort Studies
Comorbidity
Erectile Dysfunction*
Family Characteristics
Insurance Coverage
Logistic Models
Male
Multivariate Analysis
National Health Programs
Periodontal Diseases
Periodontitis*
Prevalence
Retrospective Studies
Smoke
Smoking
Smoke

Figure

• 

  Figure 1 Flow chart of the inclusion and exclusion of participants in the NHIS-NSC from 2002 to 2013. NHIS-NSC: National Health Insurance Service-National Sample Cohort, PSTP: periodontal surgery for the treatment of periodontitis, VED: vasculogenic erectile dysfunction.

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