Yeungnam Univ J Med.  1992 Dec;9(2):407-415. 10.12701/yujm.1992.9.2.407.

Intrafamilial transmission of HCV: comparison with HBV

• Lee HJ

• KMID: 2377595
• DOI: http://doi.org/10.12701/yujm.1992.9.2.407

Abstract

Among 85 patients with anti-HCV positive chronic liver disease, only 21.2% have past history of blood transfusion and over half the cases, they do not have any suspicious risk factors for HCV infection. 3 of 85 families show anti-HCV positive family members. On the other hand, 40 of 60 patients with HBsAg positive chronic liver disease show HBsAg positive family members. In Korea, HBV is transmitted mainly through vertical and intrafamilial infection but HCV disease might be rather horizontal and sporadic than vertical. To define the evident source of infection in sporadic hepatitis C, first of all, simple test with high sensitivity and specificity for diagnosis of HCV infection would be needed.

Keyword

anti-HCV; Epidemiology; Intrafamilial transmission; Sporadic infection; HBsAg

MeSH Terms

Blood Transfusion
Diagnosis
Epidemiology
Hand
Hepatitis B Surface Antigens
Hepatitis C
Humans
Korea
Liver Diseases
Risk Factors
Sensitivity and Specificity
Hepatitis B Surface Antigens