Korean J Med.
2017 Feb;92(1):66-69. 10.3904/kjm.2017.92.1.66.
Takayasu's Arteritis Presenting with Hypertension in Pulmonary Tuberculosis
- Affiliations
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- 1Division of Cardiology, Department of Internal Medicine, The Armed Forces Capital Hospital, Seongnam, Korea. kimss2866@yuhs.ac
- 2Department of General Internal Medicine, Cha Bundang Medical Center, CHA University, Seongnam, Korea.
- KMID: 2376946
- DOI: http://doi.org/10.3904/kjm.2017.92.1.66
Abstract
- Takayasu's arteritis (TA) is an inflammatory disease involving large arteries and their branches. The etiology of TA is unknown, but infectious agents and genetic factors play a significant role in its pathogenesis. A relationship between TA and Mycobacterium tuberculosis infection has been suggested, since both diseases have similar chronic inflammatory lesions and the presence of occasional granulomas in arterial walls. Patients with TA have an increased immune response to Mycobacterium tuberculosis antigens, suggesting a role for this organism in the immunopathogenesis of the disease. Herein, we present a case of TA with active pulmonary tuberculosis in a Korean patient. A 21-year-old male presented with hypertension and active pulmonary tuberculosis. TA invading the renal artery was diagnosed while evaluating hypertension. The patient was treated with prednisolone, methotrexate, anti-hypertensive medications, and anti-tuberculosis medications.
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