Korean J Gastroenterol.  2015 Mar;65(3):190-193. 10.4166/kjg.2015.65.3.190.

Atypical Image of Focal Nodular Hyperplasia: Central Defect on Hepatobiliary Phase of Liver Magnetic Resonance Imaging

Affiliations
  • 1Department of Radiology, Gachon University Gil Medical Center, Incheon, Korea. 0903gdf@gmail.com

Abstract

No abstract available.


MeSH Terms

Adult
Female
Focal Nodular Hyperplasia/*diagnosis/pathology
Gadolinium DTPA/chemistry
Hepatitis B, Chronic/diagnosis
Humans
Image-Guided Biopsy
Liver/pathology
Magnetic Resonance Imaging
Tomography, X-Ray Computed
Gadolinium DTPA

Figure

  • Fig. 1. CT images of focal nodular hyperplasia. A lesion shows strong enhancement (arrow) on arterial phase (A) and has isoattenuation (arrow) on delayed phase of dynamic contrast-enhance CT (B).

  • Fig. 2. MRI images of focal nodular hyperplasia (arrows). (A) Central scar in the lesion has bright high signal intensity on T2-weighted image of MRI. Arterial enhancement of lesion on MRI (B) is similar to that of CT scan, but on delayed image on MRI, there is peripheral enhancement and central low signal intensity (C). (D) The central portion of the lesion is noted by defect on hepatobiliary phase.


Reference

References

1. Wanless IR, Mawdsley C, Adams R. On the pathogenesis of focal nodular hyperplasia of the liver. Hepatology. 1985; 5:1194–1200.
Article
2. Nguyen BN, Fléjou JF, Terris B, Belghiti J, Degott C. Focal nodular hyperplasia of the liver: a comprehensive pathologic study of 305 lesions and recognition of new histologic forms. Am J Surg Pathol. 1999; 23:1441–1454.
3. Brancatelli G, Federle MP, Grazioli L, Blachar A, Peterson MS, Thaete L. Focal nodular hyperplasia: CT findings with emphasis on multiphasic helical CT in 78 patients. Radiology. 2001; 219:61–68.
Article
4. Kamel IR, Liapi E, Fishman EK. Focal nodular hyperplasia: lesion evaluation using 16-MDCT and 3D CT angiography. Am J Roentgenol. 2006; 186:1587–1596.
Article
5. Hussain SM, Terkivatan T, Zondervan PE, et al. Focal nodular hyperplasia: findings at state-of-the-art MR imaging, US, CT, and pathologic analysis. Radiographics. 2004; 24:3–17. discussion 18–19.
Article
6. Grazioli L, Bondioni MP, Haradome H, et al. Hepatocellular adenoma and focal nodular hyperplasia: value of gadoxetic acid-enhanced MR imaging in differential diagnosis. Radiology. 2012; 262:520–529.
Article
7. Suh CH, Kim KW, Kim GY, Shin YM, Kim PN, Park SH. The diagnostic value of Gd-EOB-DTPA-MRI for the diagnosis of focal nodular hyperplasia: a systematic review and meta-analysis. Eur Radiol. 2014. doi: 10.1007/s00330-014-3499-9.
Article
8. Eisenberg LB, Warshauer DM, Woosley JT, Cance WG, Bunzendahl H, Semelka RC. CT and MRI of hepatic focal nodular hyperplasia with peripheral steatosis. J Comput Assist Tomogr. 1995; 19:498–500.
Article
9. Fujiwara H, Sekine S, Onaya H, Shimada K, Mikata R, Arai Y. Ring-like enhancement of focal nodular hyperplasia with hep-atobiliary-phase Gd-EOB-DTPA-enhanced magnetic resonance imaging: radiological-pathological correlation. Jpn J Radiol. 2011; 29:739–743.
Article
10. Yoon JH, Kim JY. Atypical findings of focal nodular hyperplasia with gadoxetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging. Iran J Radiol. 2014; 11:e9269.
Article
11. Yoneda N, Matsui O, Kitao A, et al. Hepatocyte transporter ex-pression in FNH and FNH-like nodule: correlation with signal intensity on gadoxetic acid enhanced magnetic resonance images. Jpn J Radiol. 2012; 30:499–508.
Article
Full Text Links
  • KJG
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr