J Pathol Transl Med.  2017 Mar;51(2):180-184. 10.4132/jptm.2016.08.30.

Mucinous Cystadenoma of the Testis: A Case Report with Immunohistochemical Findings

• Kim G
• Kwon D
• Na HY
• Kim S
• Moon KC

• KMID: 2372969
• DOI: http://doi.org/10.4132/jptm.2016.08.30

Abstract

Mucinous cystadenoma of the testis is a very rare tumor. Herein, we report a case of mucinous cystadenoma arising in the testis of a 61-year-old man, along with a literature review. Computed tomography showed a 2.5-cm-sized poorly enhancing cystic mass. Grossly, the tumor was a unilocular cystic mass filled with mucinous material and confined to the testicular parenchyma. Histologically, the cyst had a fibrotic wall lined by mucinous columnar epithelium without atypia. Immunohistochemical staining was positive for cytokeratin 20 and CDX2, as well as focally positive for cytokeratin 7. The pathologic diagnosis was mucinous cystadenoma.

Keyword

Testis; Cystadenoma, mucinous; Immunohistochemistry

Figure

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  Fig. 1. Representative images of radiologic and macroscopic findings of a right testicular mass. Computed tomography (A) and ultrasound imaging (B) present a cystic mass (arrow in A) suspected to have a tumorous condition. (C) Surgical specimen reveals a mass with a unilocular cyst filled with mucinous materials.

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  Fig. 2. Microscopic findings of the mucinous cystadenoma of the testis. (A) The tumor has a uniloculated cyst with an expanding growth pattern. (B) The cyst is surrounded by a thick fibrous capsule, and there are some inflammatory cells around the tumor. (C) The cyst is filled with mucinous material. (D) The wall of the cavity is lined by a single layer of columnar mucinous epithelium, and the lining cells show no cytologic atypia. (E) Mucin extravasation into the stroma and some inflammatory cell infiltration are observed. (F) The inflammatory cells are composed of lymphocytes, plasma cells, and histiocytes.

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  Fig. 3. Immunohistochemical staining results. The lining cells are positive for cytokeratin 20 (A), focally positive for cytokeratin 7 (B), positive for CDX2 (C), and negative for PAX8 (D).

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