Korean J Obes.  2016 Dec;25(4):184-187. 10.7570/kjo.2016.25.4.184.

Prognosis of Heart Disease in Obesity – The Obesity Paradox

Affiliations
  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Inje University School of Medicine, Ilsanpaik Hospital, Goyang, Korea. jhnoh@paik.ac.kr

Abstract

Obesity increases the risk for heart diseases, including cardiovascular disease and heart failure. This is caused by the increasing prevalence of cardiovascular risk factors such as hypertension, glucose intolerance and dyslipidemia. Furthermore, obesity itself is an independent risk factor of heart disease. However, many studies and meta-analyses have shown that higher BMI correlates with better survival among patients with heart disease, known as the obesity paradox. In this review, the complex and disparate effects of obesity on heart disease and the evidence regarding pathophysiologic mechanisms of obesity-related heart disease will be discussed.

Keyword

Obesity; Heart disease; Prognosis

MeSH Terms

Cardiovascular Diseases
Dyslipidemias
Glucose Intolerance
Heart Diseases*
Heart Failure
Heart*
Humans
Hypertension
Obesity*
Prevalence
Prognosis*
Risk Factors
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