Ann Dermatol.  2014 Jun;26(3):424-425.

Gene Mutation Analysis in a Korean Patient with Early-Onset and Recalcitrant Generalized Pustular Psoriasis

Affiliations
  • 1Department of Dermatology, Ajou University School of Medicine, Suwon, Korea. esl@ajou.ac.kr
  • 2Department of Microbiology and Immunology, Ajou University School of Medicine, Suwon, Korea.

Abstract

No abstract available.


MeSH Terms

Humans
Psoriasis*

Figure

  • Fig. 1 More extensive and aggressive pustular patches (A) covering >90% of the body surface area compared to those observed in the previous attack (B).

  • Fig. 2 Mutation c.115+6T>C observed in a Korean patient (A). At the protein level, a higher expression of interleukin-36 (IL-36) is noted on keratinocytes below the pustules (B) compared to those of psoriasis vulgaris (C) (B, C: polyclonal anti-IL-36α/IL-1F6 antibody, ×200)


Reference

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