Ann Dermatol.  2014 Jun;26(3):381-384.

A Case of Isolated Bowenoid Papulosis of the Nipple

• Lee HJ
• Shin DH
• Choi JS
• Kim KH

Abstract

Bowenoid papulosis (BP) is a disease that mainly occurs in sexually active young adults. The patients present with multiple pigmented papular lesions with a verrucous surface on the anogenital area. Although extragenital BP is usually associated with concomitant genital involvement, a few cases of isolated extragenital BP have been reported. However, to our knowledge, BP of the nipple has not yet been reported in the medical literature. We report the case of a 32-year-old woman who presented with isolated extragenital BP of the nipple caused by human papillomavirus-16.

Keyword

Isolated extragenital bowenoid papulosis; Nipple

MeSH Terms

Adult
Female
Humans
Nipples*
Young Adult

Figure

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  Fig. 1 A single, 0.7×0.8 cm, dark brownish, verrucous papule on the right nipple.

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  Fig. 2 Histopathological findings. (A) Parakeratosis, acanthosis, and papillomatosis of the epidermis (H&E, ×200). (B) Atypical and dyskeratotic keratinocytes with mitotic figures and loss of orderly maturation scattered throughout the epidermis (H&E, ×40).

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  Fig. 3 Positive polymerase chain reaction for HPV-16 (red box). S: sample of patient, +: positive control, -: negative control, M: marker, HPV: human papillomavirus.

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