Ann Dermatol.  2017 Feb;29(1):114-116. 10.5021/ad.2017.29.1.114.

Tuberculosis Cutis Orificialis in Adalimumab Related Immunosupressive Patient

• Iskandarli M
• Gerceker Turk B
• Yaman B
• Ceylan N
• Ceylan C

• KMID: 2368043
• DOI: http://doi.org/10.5021/ad.2017.29.1.114

Abstract

No abstract available.

MeSH Terms

Adalimumab*
Humans
Tuberculosis*
Adalimumab

Figure

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  Fig. 1 (A) Irregular, well-demarcated ulceration with pseudomembranous base on upper gingival mucosa. (B) Healed gingival ulceration following the nine month of antituberculous therapy.

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  Fig. 2 (A) Millet seeds appearance of the lungs due to miliary tuberculous (TB) infection. (B) Hepatosplenomegaly as a manifestation of disseminated TB infection. (C) Enlarged lymph node (arrow) due to TB lymphadenitis.

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  Fig. 3 (A) Single multinuclear Langhans type giant cell without granulomatous inflammation in tissue sample taken from gingiva (H&E, ×40). (B) Granulomatous inflammation in the excised lymph node (LN) (H&E, ×40). (C) Multinuclear Langhans type giant cells around granular formations in excised posterior triangule LN (H&E, ×10). (D) Giant cells and histiocytes around caseous necrosis (H&E, ×200).

Reference

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