Ann Clin Neurophysiol.
2017 Jan;19(1):54-57. 10.14253/acn.2017.19.1.54.
Distal acquired demyelinating symmetric neuropathy associated with anti-GM1 and anti-GD1b antibodies
- Affiliations
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- 1Department of Neurology, Jeju National University School of Medicine, Jeju, Korea. neurokang@jejunu.ac.kr
- KMID: 2367996
- DOI: http://doi.org/10.14253/acn.2017.19.1.54
Abstract
- Distal acquired demyelinating symmetric (DADS) neuropathy is a variant form of chronic inflammatory demyelinating polyradiculoneuropathy. A 54-year-old man presented with gait disturbance owing to weakness in both legs. Nerve conduction studies showed demyelinating sensorimotor polyneuropathy, and laboratory studies demonstrated anti-GM1 and anti-GD1b IgG antibodies, but no anti-myelin associated glycoprotein activity. We suggest that an antiganglioside antibodies assay needs to be applied when DADS neuropathy is suspected in order to improve the classification of dysimmune neuropathies.
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